ALDOSTERONE
Aldosterone causes the distal tubule and collecting ducts to reabsorb increased levels of sodium. Aldosterone is produced in the cortex of the adrenal glands. When the adrenal glands of experimental animals are removed, too much sodium is excreted, leading to serious depletion of the extracellular fluid.

Decreased blood volume and interstitial fluid level, resulting in decreased blood pressure, trigger aldosterone secretion.