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TRANSLATION
AND tRNA
During translation, a polypeptide chain specified
by the mRNA is synthesized. Each triplet
(three-base sequence) in the mRNA constitutes
a codon, which specifies one amino acid
in the polypeptide chain, or a stop or start signal.
Translation requires tRNAs and complex cell machinery,
including ribosomes.
Transfer RNAs (tRNAs)
are the decoding molecules in the translation
process. Each tRNA molecule is specific for only
one amino acid. One part of the molecule contains
a three-base anticodon, which is complementary
to a codon of the mRNA. Attached to one end of
the tRNA molecule is the amino acid specified
by the complementary mRNA codon. Amino acids are
covalently bound to tRNA by aminoacyl-tRNA
synthetase enzymes.
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